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Yıl:2014; Cilt: 4; Sayı: 2>> Özet
TAM METİN
Journal of Mood Disorders; 2014;4(2):47-52
Orta-ileri ve genç yaş mani hastalarının karşılaştırılması
E Özkorumak, DS Aykut, A Tiryaki
Karadeniz Teknik Üniversitesi, Trabzon
Amaç: İleri yaş iki uçlu bozukluk (İUB) mani nöbetinin klinik özellikleriyle ilgili veriler sınırlıdır. Bu çalışmada ileri yaş İUB mani nöbeti ile başvuran hastaları çeşitli klinik özellikler açısından genç İUB mani nöbeti yaşayan hastalar ile karşılaştırmak ve mani nöbetinin ileri yaş hastalarda klinik görünümünün tanımlanmasına katkıda bulunmak amaçlanmıştır. Yöntem: İUB mani nöbeti belirtileri ile bir üniversite hastanesi ve ruh sağlığı hastanesi psikiyatri kliniklerine başvuran 50 yaş üstü 25 ileri yaş hasta ve 30 yaş altı 25 genç hasta çalışmaya alınmıştır. İUB mani nöbeti tanısı DSM-IV Eksen I Bozuklukları için Yapılandırılmış Klinik Görüşme (SCID-I) uygulanarak konulmuştur. İUB tanısı konulan hastaları değerlendirmek için Young Mani Ölçeği (YMRS) ve Montgomery Asberg Depresyon Değerlendirme Ölçeği uygulanmıştır. Bulgular: İki grup arasında cinsiyet açısından anlamlı fark yoktur. Hastalık başlangıç yaşı ileri yaş grubunda anlamlı derecede daha ileridir. İleri yaş grubunda eğitim düzeyi anlamlı olarak düşük iken, çalışma durumu açısından gruplar arasında fark yoktur. YMRS değeri ileri yaş hastalarda anlamlı olarak daha yüksektir. Başvuru sırasında bildirilen saldırganlık şikayeti genç hastalarda anlamlı olarak daha yüksek sıklıkta görülmektedir. Tek duygudurum düzenleyici kullanımı ileri yaş hastalarda daha yüksek orandadır. Sonuç: İleri yaş İUB mani nöbeti hastaları çeşitli klinik özellikler açısından genç hastalardan farklılık göstermekle birlikte ileri yaş hastalarda mani nöbetinin özgün özelliklerine odaklanacak ileri çalışmalara ihtiyaç duyulmaktadır.
Comparison of moderate-to-advanced aged with young manic patients
Objective: The data about clinical features on Bipolar Disorder-type I manic episode in the elderly individuals is limited. This article aims to compare patients admitted for manic episode in moderate-to-advanced aged patients with the young patients in terms of various clinical features and contribute describing clinical features of manic episode in elderly individuals. Method: Twenty-five patients older than 50 years old and 25 patients younger than 30 years old with manic episode who admitted to an university and a mental health hospital were included the study. The diagnosis of Bipolar Disorder manic episode was made with Structured Clinical Interview for DSM-IV (SCID-I). The Young Mania Scale and Montgomery Asberg Rating Scale were performed to assess the patienst with bipolar I disorder. Results: The gender ratio did not differ between the two groups. The age at onset of the illness was later in elderly patients. The level of education was significantly lower in moderate-to-advanced aged patients, but there was no difference in working status between moderate-to-advanced aged and young patients. Score of YMRS was significantly higher in moderate-to-advanced aged patients. Agressiveness was significantly higher in ratio among the admitting symptoms in young patients. Use of mood stabilizers as monotheraphy was significantly higher in elderly patients. Conclusion: The moderate-to-advanced aged patients with bipolar disorder manic episode show different features than younger patients in terms of some clinical features but further studies are needed for focusing more specialized features of manic episode in moderate-to-advanced aged patients.

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