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Yıl:2013; Cilt: 3; Sayı: Ek 1>> Özet
TAM METİN
Journal of Mood Disorders; 2013;3(Ek 1):17-19
İki uçlu bozuklukta özel gruplarda tedavi yaklaşımı: Gebelik ve lohusalık
Ç Hocaoğlu
Recep Tayyip Erdoğan Üniversitesi, Rize
Pek çok ilaç (tedavi) seçeneğinin gebelikteki etkileri bilinmemekte ve bazıları teratojen olarak kabul edilmektedir. Bu yüzden gebe hastaları psikotrop ajanlarla tedavi etme kararı etik bir çıkmazı çözmeyi gerektirir. Risk-yarar kararı alınırken hem iki uçlu bozukluğun yineleme riski ile beraberinde getirdiği morbidite hem de fetusun psikotrop ilaçlara maruz kalmasının riskleri göz önünde bulundurulmalıdır. Bunlara ek olarak lohusalıkta hastalık yineleme riski çarpıcı bir biçimde artmaktadır. Tüm psikotrop ilaçların bir ölçüde anne sütüne geçtiği oldukça iyi bilinmektedir. Bu yüzden emziren bir anneye ilaç başlanırken bu psikotrop ilaçların bebek üzerindeki etkileri göz önünde bulundurulmalıdır. Bu yazıda psikotrop ilaçların hamilelik ve lohusalık dönemindeki iki uçlu bozukluk olgularında kullanımına yönelik literatür gözden geçirilmiş ve ayrıca bu alanda geliştirilmiş olan bazı pratik bilgiler sunulmuştur.
Approach to treatment of bipolar disorder in special populations: pregnancy and the postpartum period
The effects of pharmacological treatment on obstetrical outcome are not well known and some of these agents are considered teratogenic. Thus, the decision to treat pregnant patients with psychotropic agents requires solving an ethical dilemma. Risk-benefit decisions should be made while considering both the risk of relapse of bipolar disorder and its morbidity, and the risk of fetal exposure to psychotropic medications. Moreover, the risk of recurrence increases dramatically in the postpartum period. It is also well known that all of the psychotropic medications that are studied before are passed thorough to the breast milk, therefore while prescribing for a breastfeeding woman the effects on infants should be considered. In this REVIEW , the use of psychotropic drugs in patients with bipolar disorder in pregnancy and in postpartum period are represented regarding to some practical applications.

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